Artificial intelligence (AI), including advanced GenAI and Large Language Models, offer groundbreaking potential for supply chains,dramatically improving forecasting, decision-making, and operational efficiency. Yet, despite its promise, many organizations face significant challenges achieving widespread adoption and tangible business benefits.Why does this gap persist? Because successful AI implementation isn't merely about technology,it's fundamentally about people, processes, and readiness. In this engaging and practical keynote, we'll unpack recent research revealing critical yet overlooked adoption factors, including data literacy, effective communication, managing cognitive workloads, and ensuring AI decision-making transparency. You'll learn how these elements shape user trust and determine real-world AI effectiveness. Drawing from industry examples and emerging insights from advanced adoption models, attendees will gain actionable guidance for overcoming common barriers. Leave equipped to build stronger human-AI partnerships, boost organizational readiness, and fully unlock AI's transformative potential in your own supply chain and operational environments.